Search on: COA SYNTHETASES, SUCCINYL 
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Descriptor English:   Succinate-CoA Ligases 
Descriptor Spanish:   Succinato-CoA Ligasas 
Descriptor Portuguese:   Succinato-CoA Ligases 
Synonyms English:   CoA Synthetases, Succinyl
Ligases, Succinate-CoA
Succinate CoA Ligases
Synthetases, Succinyl CoA
Thiokinases, Succinic
Succinic Thiokinases
Succinyl CoA Synthetases
Succinyl Coenzyme A Synthetases
Succinate-CoA Ligase (GDP-Forming)
Succinate-CoA Ligases (ADP-Forming)  
Tree Number:   D08.811.464.267.500.600
Definition English:   Enzymes that catalyze the first step leading to the oxidation of succinic acid by the reversible formation of succinyl-CoA from succinate and CoA with the concomitant cleavage of ATP to ADP (EC 6.2.1.5) or GTP to GDP (EC 6.2.1.4) and orthophosphate. Itaconate can act instead of succinate and ITP instead of GTP.EC 6.2.1.-. 
History Note English:   98(76) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   13775 
Unique Identifier:   D013389 

Occurrence in VHL: 		 

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